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KMID : 0387719940050010017
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Korean Journal of Blood Transfusion
1994 Volume.5 No. 1 p.17 ~ p.23
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Relationship Between anti-HCV with ALT Level and Follow up Study in Anti-HCV Positive Donors
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Abstract
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A prevalence of anti-HCV and ALT value was analyzed in 89.995 healthy Korean blood donors. The positive rate of anti-HCV was 0.43% (386) and increased with age. And the positive rates of anti-HCV was statistically significant higher in group
having
elevated ALT level than in group having normal ALT level (P<0.005). The mixed-infection rates of the hepatitis B and C was 0.02% (25/89,995), and statistically the positivity of anti-HCV was higher in HBs Ag positive group than in HBs Ag negative
group
(P<0.01). On follow up study from 51 donors of the anti-HCV positivity in initial test, 15(29.4%) cases were continuously positive by follow up test in 5-20 months. But these results were independent of transfusional history and intervals of
follow
up.
The positive rates of anti-HCV during the follow up with reagents of Ortho-Ⅰ and Ortho-Ⅱ were 24% and 33% respectively. The positivity of anti-HCV was higher in group had continuously elevated serum ALT level than in group with normal serum ALT
level.
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KEYWORD
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